Sildenafil treatment of women with antidepressant-associated sexual dysfunction: A randomized controlled trial. Women taking the “blue pill” (sildenafil citrate): such a big deal? Label: Vtleesi - bremelanotide injection.Label: Viagra - sildenafil citrate tablet, film coated.Label: Addyi - flibanserin tablet, film coated.FDA approves new treatment for hypoactive sexual desire disorder in premenopausal women. Sexual dysfunction in women: A practical approach. The first FDA-approved treatment for female sexual interest/arousal disorder in premenopausal women. Efficacy and safety of sildenafil citrate in women with sexual dysfunction associated with female sexual arousal disorder You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Research suggests that Addyi and Vyleesi offer small benefits to premenopausal women with sexual arousal disorders. It can also cause nausea and isolated spots of skin lightening (focal hyperpigmentation). Side effects of Vyleesi include temporary increase in blood pressure and decrease in heart rate. These effects can be intensified if you take birth control pills or drink alcohol. Side effects of Addyi include low blood pressure, fainting, and nausea. They seem to affect certain pathways in the brain that influence sexual desire. Addyi and Vyleesi treat sexual desire, though the exact mechanism of action isn’t clear. Specifically, it’s for low sexual desire that causes distress, but is unrelated to: You inject it under the skin on your abdomen or thigh about 45 minutes before you plan to have sex.īoth medications are approved to treat acquired, generalized sexual desire disorder in premenopausal women. You take one pill every day at bedtime.Īnother medication, Vyleesi, is a brand name for bremelanotide. But these are different drugs with different missions.Īddyi is a brand name for a non-hormonal medication called flibanserin. Because it’s a pink tablet and Viagra is a blue tablet, the nickname “female Viagra” was bound to happen. There are, however, a few FDA-approved medications to treat low sexual desire in women. Viagra is a brand name and there’s no “Viagra for women.” Viagra is an ED medication that improves blood flow to the penis. In studies that have included women, it appears to be fairly well-tolerated. While Viagra appears to be safe for most men, there’s little data on safety in women, particularly in the long term. That can be a problem if you already have low blood pressure or take medicines that lower blood pressure. Viagra may cause blood pressure to drop, especially within a few hours of taking it. More research is needed to fully understand if women can expect any benefit from Viagra. But that wasn’t the case for women whose sexual arousal disorder is linked to neurological or vascular problems.Ī randomized clinical trial in 2002 compared sildenafil to placebo in pre- and post-menopausal women. Some study participants experienced improved arousal, vaginal lubrication, and orgasm. There’s “inconsistent or limited-quality patient-oriented evidence” for this, according to a 2015 article authored by Mayo Clinic doctors.Ī 2014 review article noted a study of postmenopausal women with sexual arousal disorder. The women who took Viagra reported better results than those who took a placebo. Results showed that Viagra may help reduce adverse sexual effects of SSRIs and SNRIs. The study received funding by Pfizer, the maker of Viagra. serotonin-norepinephrine reuptake inhibitors (SNRIs)Ī small, randomized controlled trial in 2008 involved women with depression who took these drugs and experienced sexual dysfunction. selective serotonin reuptake inhibitors (SSRIs).One thing that can suppress libido is the use of certain antidepressants, specifically: Often, there are multiple contributing factors. It helps to understand that sexual dysfunction in women is a complex issue. Studies on its effectiveness in women have had mixed results. That may help increase sensitivity, arousal, and orgasmic function. Women who take it might also have increased blood flow to the genitals. We know that in men, Viagra dilates blood vessels and increases the flow of blood to the penis. PDE5 is an enzyme that affects blood flow. Viagra is a phosphodiesterase type 5 (PDE5) inhibitor.
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